Helical Buckling in Filopodia
نویسندگان
چکیده
منابع مشابه
Helical buckling of actin inside filopodia generates traction.
Cells can interact with their surroundings via filopodia, which are membrane protrusions that extend beyond the cell body. Filopodia are essential during dynamic cellular processes like motility, invasion, and cell-cell communication. Filopodia contain cross-linked actin filaments, attached to the surrounding cell membrane via protein linkers such as integrins. These actin filaments are thought...
متن کاملDynamic buckling of actin within filopodia
Filopodia are active tubular structures protruding from the cell surface which allow the cell to sense and interact with the surrounding environment through repetitive elongation-retraction cycles. The mechanical behavior of filopodia has been studied by measuring the traction forces exerted on external substrates.(1) These studies have revealed that internal actin flow can transduce a force ac...
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We investigate the emergence of chiral meso-structures in one-dimensional fluids consisting of stacked discotic particles and demonstrate that helical undulations are generated spontaneously from internal elastic stresses. The stability of these helical conformations arises from an interplay between long-ranged soft repulsions and nanopore confinement which is naturally present in columnar liqu...
متن کاملFilopodia
What are they? Filopodia are thin, dynamic cell extensions comprising tight bundles of long actin filaments covered with cell membrane. They can change their length rapidly, span many cell diameters, and interact with other cells. Sometimes the name filopodia is used more broadly to describe a range of cytoskeletal protrusions including thick filopodia, cell feet, and amoebae pseudopods. These ...
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We study the primary root growth of wild-type Medicago truncatula plants in heterogeneous environments using 3D time-lapse imaging. The growth medium is a transparent hydrogel consisting of a stiff lower layer and a compliant upper layer. We find that the roots deform into a helical shape just above the gel layer interface before penetrating into the lower layer. This geometry is interpreted as...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2015
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2014.11.771